We are horrified and condemn the harassment and murder of innocent Black men, women, and children across this country. There is no middle ground in our commitment to being anti-racist, and as PI, I must strive to be a stronger listener, learner, ally, and advocate. Many of our closest Black colleagues rightfully question whether the current events will really translate to systemic change, in science and beyond. We cannot let complacency rule, and instead need to examine our own roles and privileges towards identifying how to contribute to actionable change. How can we help address discrimination in admissions processes? Funding? Hiring? How can we help create a more diverse lab, student body, and faculty, both now and for the future? Can we help remake the very walls we work in, which currently display almost exclusively white, male faces? As a lab, we are committed to fighting racism in all forms. We will work to notice and call out everything from microaggressions to overt bias, at all levels, in our lab, at Penn, and beyond. As PI, I will work hard to model this at all times. We are committed to meaningful change in science and society. These are not topics to only discuss in hushed voices, but instead to loudly fight for; our system needs reinvention, not fixing.